Seanol® for Diabetes Complications
In addition to lower blood sugar and fat, Seanol® may help to prevent diabetes complications by (1) protecting blood vessels, (2) lowering blood cholesterol, and (3) promoting weight loss.
Seanol® can protect blood vessels
High blood sugar levels can be damaging to blood vessels. Inflammation and oxidative stress occurring in blood vessel cells can contribute to many diabetes complications such as atherosclerosis, kidney damage, retinopathy and nerve damage.
Several studies have shown that Seanol® can lower inflammation and reactive oxygen species (ROS) in blood vessel cells under high glucose conditions [1,2,3].
Seanol® is also a highly potent natural antioxidant. It is 230 times more effective than vitamin E, and can be absorbed easily and stay inside the body to relieve oxidative stress. Seanol® directly scavenges reactive oxygen species [4,5,6,7,8,9] and reduces ROS levels inside cells [10,3,11]. It may also help to prevent DNA from oxidative damage [9] and prevent cell death [10].
Seanol® prevents cholesterol buildup
Cholesterol build-up in vessels is another dangerous risk factor for atherosclerosis, stroke, heart attack and other related diseases. In blood tests, high LDL-cholesterol levels indicate high amounts of cholesterol entering the body, whereas high HDL-cholesterol levels in the blood indicate that cholesterol is being removed from the blood. It is recommended to keep LDL cholesterol levels below 100mg/dL, and low HDL levels are a hallmark of metabolic syndrome.
In 2 human studies, Seanol® increased HDL levels by 13.3%, and decreased LDL cholesterol by 9.3% compared to placebos [12,13]. It also decreased the risk index for atherosclerosis.
By lowering inflammation, oxidative stress and cholesterol levels in blood vessels, Seanol® may help to improve blood circulation and prevent diabetes complications.
Summary
Seanol® helps to lower inflammation and oxidative stress, which can damage and block blood vessels in a high blood sugar environment
Seanol® also lowers cholesterol levels in the blood, according to 2 human studies
Sources:
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https://dx.doi.org/10.3746/pnf.2014.19.3.170
https://dx.doi.org/10.1016/j.tiv.2009.11.002
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https://dx.doi.org/10.1016/j.foodchem.2013.04.019
https://dx.doi.org/10.1016/j.fra.2013.10.006
https://dx.doi.org/10.1177/1082013206062422
https://dx.doi.org/10.3390/md11010165
https://www.koreascience.or.kr/article/JAKO200509905834275.pdf
https://dx.doi.org/10.3109/10715762.2013.797080
https://dx.doi.org/10.1016/j.bmc.2009.01.031
https://dx.doi.org/10.1002/ptr.3559
https://dx.doi.org/10.1089/jmf.2011.1996